Researchers at the University of Salento in Lecce, Italy have discovered two new cannabionoids; THCP and CBDP. THCP is estimated to be even more potent than THC. In tests on mice, researchers found THCP has “an affinity for CB1 receptor more than thirty-fold higher compared to the one reported for THC.”
The other newly discovered cannabionoid, CBDP does not show promise in binding to the CB1 or CB2 receptors in the body’s endocannabinoid system and is will not be further researched at this time. The study found that CBDP is similar to CBD. However, researchers claim THCP is 30 times more potent than THC. This alleged stronger potency has not been determined to cause a more intense high than THC, but the mice in the study showed that THCP were more active than lower doses of THC.
This new research now brings the total number of discovered cannabinoids to 150. It is possible there are more. Researchers note that “most of them have neither been isolated nor characterized.” The new cannabinoids “were isolated and fully characterized” by researchers.
Cannabinoids and their varying effects on the body are the reason different strands of marijuana produce different effects on the body. The amounts of cannabinoids vary depending on the cannabis plant, which leads researchers to speculate levels of THCP and CBDP might be higher in other strands of plants.
The study has not determined the benefits of the new cannabinoids. Their discovery shows that we still have much to learn about the effects and benefits of cannabis.